Dopaminergic Antiparkinsonism Agents

*Prices reflect U.S. average retail price

Sinemet (carbidopa/levodopa)

Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. It is primarily used to manage the symptoms of Parkinson's disease but does not change the course of the disease... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                                Average retail cost: $176/month

Cycloset (bromocriptine)

Bromocriptine (originally marketed as Parlodel, subsequently under many names) is an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes... Wikipedia

 

 

Manufacturer's Website: Cycloset                                                                                                                                Average retail cost: $404/month

Mirapex (pramipexole)

Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome ... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                             Average retail cost: $242/month

Rytary (carbidopa/levodopa)

Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. It is primarily used to manage the symptoms of Parkinson's disease but does not change the course of the disease... Wikipedia

 

 

Manufacturer's Website: Rytary                                                                                                                            Average retail cost: $451/month

Stalevo 100 (carbidopa/entacapone/levodopa)

Carbidopa/levodopa/entacapone, sold under the brand name Stalevo, is an anti-parkinsonian dopaminergic combination medication that contains carbidopa, levodopa, and entacapone for the treatment of Parkinson's disease... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                            Average retail cost: $815/month

Mirapex ER (pramipexole)

Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome ... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                 Average retail cost: $856/month

Neupro (rotigotine)

Rotigotine (Neupro) is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours ... Wikipedia

 

 

Manufacturer's Website: Neupro                                                                                                                           Average retail cost: $952/month

Azilect (rasagiline)

Rasagiline (Azilect, TVP-1012, N-propargyl-1(R)-aminoindan) is an irreversible inhibitor of monoamine oxidase-B used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases ... Wikipedia

 

 

Manufacturer's Website: Azilect                                                                                                                          Average retail cost: $1,188/month

Comtan (entacapone)

Entacapone, sold under the brand name Comtan among others, is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Entacapone together with levodopa and carbidopa allows levodopa to have a longer effect in the brain and reduces Parkinson’s disease signs and symptoms for a greater length of time than levodopa and carbidopa therapy alone ... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                              Average retail cost: $975/month

Stalevo 200 (carbidopa/entacapone/levodopa)

Carbidopa/levodopa/entacapone, sold under the brand name Stalevo, is an anti-parkinsonian dopaminergic combination medication that contains carbidopa, levodopa, and entacapone for the treatment of Parkinson's disease... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                          Average retail cost: $964/month

Apokyn (apomorphine)

Apomorphine (brand names Apokyn, Ixense, Spontane, Uprima) is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors... Wikipedia

 

 

Manufacturer's Website: Apokyn                                                                                                                                Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

Emsam (selegiline)

Selegiline, also known as L-deprenyl, is a substituted phenethylamine. At normal clinical doses, it is a selective irreversible MAO-B inhibitor. In larger doses it loses its specificity and also inhibits MAO-A. It is available in pill form under many brand names and is used to reduce symptoms in early-stage Parkinson's disease. A transdermal patch (brand name, Emsam) is used to treat depression... Wikipedia

 

 

Manufacturer's Website: Emsam                                                                                                                               Average retail cost: $2,368/carton

Zelapar (selegiline)

Selegiline, also known as L-deprenyl, is a substituted phenethylamine. At normal clinical doses, it is a selective irreversible MAO-B inhibitor. In larger doses it loses its specificity and also inhibits MAO-A. It is available in pill form under many brand names and is used to reduce symptoms in early-stage Parkinson's disease. A transdermal patch (brand name, Emsam) is used to treat depression... Wikipedia

 

 

Manufacturer's Website: Zelapar                                                                                                                               Average retail cost: $4,462/month

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