Histone Deacetylase Inhibitors

Zolinza (vorinostat)

Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities. Vorinostat is marketed under the name Zolinza (/zoʊˈlɪnzə/ zoh-LIN-zə) by Merck for the treatment of cutaneous manifestations in patients with cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after two systemic therapies

...Wikipedia

 

 

Manufacturer's Website: Zolinza                                                                                                                                   Average retail cost: $6,107/42 caps

Beleodaq (belinostat)

Belinostat (trade name Beleodaq, previously known as PXD101) is a histone deacetylase inhibitor drug developed by TopoTarget for the treatment of hematological malignancies and solid tumors. It was approved in July 2014 by the US FDA to treat peripheral T-cell lymphoma.

...Wikipedia

 

Manufacturer's Website: Beleodaq                                                                                                                                  Average retail cost: *

 

*This drug is administered by your healthcare practitioner, which usually means it may be expensive.

Istodax (romidepsin)

Romidepsin, also known as Istodax, is an anticancer agent used in cutaneous T-cell lymphoma (CTCL) and other peripheral T-cell lymphomas (PTCLs)...Wikipedia

 

 

Manufacturer's Website: Istodax                                                                                                                                    Average retail cost: *

 

*This drug is administered by your healthcare practitioner, which usually means it may be expensive.

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