*Prices reflect U.S. average retail price

Diphenhydramine is an antihistamine mainly used to treat allergies. It is also used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea... Wikipedia

Manufacturer's Website: Not Available                                                                                                                       Average retail cost: $11/month

Zolpidem, sold under the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping. It is typically only recommended if sleep hygiene is not effective. It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer... Wikipedia

Manufacturer's Website: Not Available                                                                                                                      Average retail cost: $83/month

Zaleplon (marketed under the brand names Sonata, Starnoc, and Andante) is a sedative-hypnotic, almost entirely used for the management/treatment of insomnia. It is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class... Wikipedia

Manufacturer's Website: Not Available                                                                                                               Average retail cost: $482/month

Suvorexant, sold under the trade name Belsomra, is a medication for the treatment of insomnia. It is effective for insomnia, at least for four weeks and as compared to a placebo... Wikipedia

Manufacturer's Website: Belsomra                                                                                                                  Average retail cost: $503/month

Zolpidem, sold under the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping. It is typically only recommended if sleep hygiene is not effective. It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer... Wikipedia

Manufacturer's Website: Not Available                                                                                                                 Average retail cost: $407/month

Zolpidem, sold under the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping. It is typically only recommended if sleep hygiene is not effective. It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer... Wikipedia

Manufacturer's Website: Not Available                                                                                                                               Average retail cost: $501/month

Ramelteon, marketed as Rozerem among others, is a sleep agent that selectively binds to the MT1 and MT2 receptors in the suprachiasmatic nucleus (SCN), instead of binding to GABAA receptors, such as with drugs like zolpidem.

It however does not appear to speed the onset of sleep or the amount of sleep a person gets. It is approved by the U.S. Food and Drug Administration (FDA) for long-term use.

Ramelteon does not show any appreciable binding to GABAA receptors, which are associated with anxiolytic, myorelaxant, and amnesic effects

... Wikipedia

Manufacturer's Website: Rozerem                                                                                                                               Average retail cost: $461/month

Eszopiclone, marketed by Sunovion under the brand-name Lunesta, is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia

... Wikipedia

Manufacturer's Website: Not Available                                                                                                                    Average retail cost: $814/month

Doxepin is a tricyclic antidepressant (TCA) used as a pill to treat major depressive disorder, anxiety disorders, chronic hives, and for short-term help with trouble remaining asleep after going to bed (a form of insomnia). As a cream it is used for short term treatment of itchiness due to atopic dermatitis or lichen simplex chronicus... Wikipedia

Manufacturer's Website: Silenor                                                                                                                      Average retail cost: $639/month

Zolpidem, sold under the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping. It is typically only recommended if sleep hygiene is not effective. It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer... Wikipedia

Manufacturer's Website: Ambien                                                                                                                     Average retail cost: $762/month

Zolpidem, sold under the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping. It is typically only recommended if sleep hygiene is not effective. It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer... Wikipedia

Manufacturer's Website: Ambien                                                                                                                         Average retail cost: $764/month

Sodium oxybate (USAN; sodium γ-hydroxybutyrate; brand names Xyrem, Alcover, Anetamin, Gamanest, Gioron, Somsanit) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of excessive daytime sleepiness (EDS) associated with narcolepsy, and by the FDA, Health Canada and in some areas of the United Kingdom National Health Service  for the treatment of cataplexy associated with narcolepsy... Wikipedia

Manufacturer's Website: Xyrem                                                                                                                             Average retail cost: $13,214/bottle

Tasimelteon (trade name Hetlioz) is a drug approved by the U.S. Food and Drug Administration (FDA) in January 2014 for the treatment of non-24-hour sleep–wake disorder (also called Non-24, N24 and N24HSWD). In June 2014, the European Medicines Agency accepted an EU filing application for tasimelteon and in July 2015, the drug was approved in Europe for the treatment of non-24-hour sleep-wake rhythm disorder in totally blind adults, but not in the rarer case of non-24 in sighted people... Wikipedia

Manufacturer's Website: Hetlioz                                                                                                                            Average retail cost: $17,231/month

Dexmedetomidine, sold under the trade name Precedex among others, is a drug used in humans for sedation. Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. It is also used in humans to treat acute agitation associated with schizophrenia or bipolar I or II disorder... Wikipedia

Manufacturer's Website: Igalmi                                                                                                                            Average retail cost: *

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.