NK1 Receptor Antagonists

*Prices reflect U.S. average retail price

Varubi (rolapitant)

Rolapitant (INN, trade name Varubi  in the US and Varuby in Europe) is a drug originally developed by Schering-Plough and licensed for clinical development by Tesaro, which acts as a selective NK1 receptor antagonist (antagonist for the NK1 receptor). It has been approved as a medication for the treatment of chemotherapy-induced nausea and vomiting (CINV) after clinical trials showed it to have similar or improved efficacy and some improvement in safety over existing drugs for this application... Wikipedia

 

 

Manufacturer's Website: Varubi                                                                                                                            Average retail cost: $813/2 tabs

Emend (aprepitant)

Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.

Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting... Wikipedia

 

 

Manufacturer's Website: Emend                                                                                                                         Average retail cost: $146/1 cap

Emend for Injection (fosaprepitant)

Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.

Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting... Wikipedia

 

 

Manufacturer's Website: Emend                                                                                                                           Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

 

Copyright  2006---2023  Automated Clinical Guidelines, LLC.  All rights reserved.