Anticoagulant Reversal Agents

*Prices reflect U.S. average retail price

Mephyton (phytonadione)

Phytomenadione, also known as vitamin K1 or phylloquinone, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat certain bleeding disorders. This includes warfarin overdose, vitamin K deficiency, and obstructive jaundice...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                  Average retail cost: $97/tablet

Andexxa (coagulation factor Xa)

FACTOR XA is used to reverse the blood-thinning effect of apixaban or rivaroxaban in emergency situations.

 

 

Manufacturer's Website: Andexxa                                                                                                                                         Average retail cost:*

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Praxbind (idarucizumab)

Idarucizumab, sold under the brand name Praxbind, is a monoclonal antibody used as a reversal agent for dabigatran. Idarucizumab was developed by Boehringer Ingelheim. One study sponsored by the manufacturer found that idarucizumab effectively reversed anticoagulation caused by dabigatran within minutes... Wikipedia

 

 

Manufacturer's Website: Praxbind                                                                                                                                         Average retail cost:*

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

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