Calcineurin Inhibitors

*Prices reflect U.S. average retail price

Neoral (cyclosporine)

Cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is a natural product. It is taken by mouth or by injection into a vein for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. It is also used as eye drops for keratoconjunctivitis sicca (dry eyes)...Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                          Average retail cost: $372/30 caps

Hecoria (tacrolimus)

Tacrolimus,  is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and dogs...Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                          Average retail cost: $736/60 caps

Prograf (tacrolimus)

Tacrolimus,  is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and dogs...Wikipedia

 

Manufacturer's Website: Prograf                                                                                                                                      Average retail cost: $1,534/180 caps

Gengraf (cyclosporine)

Cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is a natural product. It is taken by mouth or by injection into a vein for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. It is also used as eye drops for keratoconjunctivitis sicca (dry eyes)...Wikipedia

 

Manufacturer's Website: Gengraf                                                                                                                               Average retail cost: $474/60 caps

Astagraf XL (tacrolimus)

Tacrolimus,  is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and dogs...Wikipedia

 

Manufacturer's Website: Astragraf                                                                                                                              Average retail cost: $583/90 caps

Sandimmune (cyclosporine)

Cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is a natural product. It is taken by mouth or by injection into a vein for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. It is also used as eye drops for keratoconjunctivitis sicca (dry eyes)...Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                 Average retail cost: $734/30 caps

Envarsus XR (tacrolimus )

Tacrolimus,  is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and dogs...Wikipedia

 

Manufacturer's Website: Envarsus XR                                                                                                                     Average retail cost: $734/90 tabs

Lupkynis (voclosporin)

Voclosporin, sold under the brand name Lupkynis, is a calcineurin inhibitor used as an immunosuppressant medication. It was approved by the U.S. Food and Drug Administration (FDA) for the treatment of lupus nephritis (LN) in January 2021...Wikipedia

 

Manufacturer's Website: Lupkynis                                                                                                                                   Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

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