Agents for Hypertensive Emergencies

*Prices reflect U.S. average retail price

Proglycem (diazoxide)

Diazoxide (INN; brand name Proglycem) is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels, preventing calcium flux across the sarcolemma and activation of the contractile apparatus. In the United States, this agent is only available in the oral form and is typically given in hospital settings... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                Average retail cost: $452/bottle

Corlopam (fenoldopam)

Fenoldopam is used as an antihypertensive agent postoperatively, and also intravenously (IV) to treat a hypertensive crisis... Wikipedia

 

Manufacturer's Website: Corlopam                                                                                                                      Average retail cost: *

 

 

* This prescription is for intravenous use in hospitalized patients only. It cannot be filled in a pharmacy and may be expensive.

Hyperstat (diazoxide)

Diazoxide (INN; brand name Proglycem) is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels, preventing calcium flux across the sarcolemma and activation of the contractile apparatus. In the United States, this agent is only available in the oral form and is typically given in hospital settings... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                                 Average retail cost: *

 

 

* This prescription is for intravenous use in hospitalized patients only. It cannot be filled in a pharmacy and may be expensive.

Nipride RTU (nitroprusside)

Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding. It is used by continuous injection into a vein. Onset is typically immediate and effects last for up to ten minutes.... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                               Average retail cost: *

 

 

* This prescription is for intravenous use in hospitalized patients only. It cannot be filled in a pharmacy and may be expensive.

Nitropress (nitroprusside)

Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding. It is used by continuous injection into a vein. Onset is typically immediate and effects last for up to ten minutes.... Wikipedia

 

Manufacturer's Website: Nitropress                                                                                                                              Average retail cost: *

 

 

* This prescription is for intravenous use in hospitalized patients only. It cannot be filled in a pharmacy and may be expensive.

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