*Prices reflect U.S. average retail price

Ivabradine, marketed under the trade name Corlanor among others, is a medication used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers... Wikipedia

Manufacturer's Website: Corlanor                                                                                                            Average retail cost: $678/month

Sotagliflozin, sold under the brand name Inpefa among others, is a medication used to reduce the risk of death due to heart failure... Wikipedia

Manufacturer's Website: Inpefa                                                                                                          Average retail cost: $717/30 tabs

Icatibant, trade name Firazyr, is medication that has been approved by the European Commission for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. It is not effective in angioedema caused by medication from the ACE inhibitor class, as shown in a 2017 trial... Wikipedia

Manufacturer's Website: Firazyr                                                                                                                Average retail cost: $11,150/month

Metirosine (INN and BAN; α-Methyltyrosine, Metyrosine USAN, AMPT) is an antihypertensive drug. It inhibits the enzyme tyrosine hydroxylase and, therefore, catecholamine synthesis, which, as a consequence, depletes the levels of the catecholamines dopamine, adrenaline and noradrenaline in the body... Wikipedia

Manufacturer's Website: Demser                                                                                                                            Average retail cost: $56,000/month

Sparsentan, sold under the brand name Filspari, is a medication used for the treatment of primary immunoglobulin A nephropathy... Wikipedia

Manufacturer's Website: Filspari                                                                                                                            Average retail cost: *

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.