Miscellaneous Central Nervous System Agents

*Prices reflect U.S. average retail price

Namenda XR (memantine)

Memantine is used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors. It was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes; the NMDA activity was discovered in the 1980s... Wikipedia

 

 

Manufacturer's Website: Namenda                                                                                                                     Average retail cost: $573/month

Namenda (memantine)

Memantine is used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors. It was first synthesized by Eli Lilly and Company in 1968 as a potential agent to treat diabetes; the NMDA activity was discovered in the 1980s... Wikipedia

 

 

Manufacturer's Website: Namenda                                                                                                              Average retail cost: $532/month

Addyi (flibanserin)

Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three. The certainty of the estimate is low. The side effects of dizziness, sleepiness, and nausea occur about three to four times more often... Wikipedia

 

 

Manufacturer's Website: Addyi                                                                                                                    Average retail cost: $864/month

Nuedexta (dextromethorphan/quinidine)

Dextromethorphan/quinidine (trade name Nuedexta) is a combination drug containing dextromethorphan and the class I antiarrhythmic agent quinidine. It is the first FDA-approved drug for the treatment of pseudobulbar affect (PBA)... Wikipedia

 

 

Manufacturer's Website: Nuedextra                                                                                                                    Average retail cost: $1,830/month

Rilutek (riluzole)

Riluzole (marketed as Rilutek and Teglutik) is a drug used to treat amyotrophic lateral sclerosis. Riluzole delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase survival by approximately two to three months... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                               Average retail cost: $4,062/month

Ampyra (dalfampridine)

4-Aminopyridine (4-AP, fampridine, dalfampridine) is an organic compound with the chemical formula C5H4N–NH2. The molecule is one of the three isomeric amines of pyridine. It is used as a research tool in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease... Wikipedia

 

 

Manufacturer's Website: Ampyra                                                                                                                                   Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

Relyvrio (sodium phenylbutyrate/taurursodiol)

Sodium phenylbutyrate/ursodoxicoltaurine, also known as sodium phenylbutyrate/taurursodiol and sold under the brand name Relyvrio among others, is a fixed-dose combination medication used for the treatment of amyotrophic lateral sclerosis (ALS)... Wikipedia

 

 

Manufacturer's Website: Relyvrio                                                                                                                          Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

Daybue (trofinetide) oral solution

Trofinetide, sold under the brand name Daybue, is a medication used for the treatment of Rett syndrome... Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                      Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

Bridion (sugammadex)

Sugammadex (Org 25969, tradename Bridion) is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA)... Wikipedia

 

 

Manufacturer's Website: Bridion                                                                                                                                   Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Leqembi (lecanemab‐irmb)

Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody medication used for the treatment of Alzheimer's disease... Wikipedia

 

 

Manufacturer's Website: Leqembi                                                                                                                                   Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

 Qalsody (tofersen)

Tofersen, sold under the brand name Qalsody, is a medication used for the treatment of amyotrophic lateral sclerosis (ALS). Tofersen is an antisense oligonucleotide that targets the production of superoxide dismutase 1, an enzyme whose mutant form is commonly associated with ALS. It is administered as an intrathecal injection into the spinal cord... Wikipedia

 

 

Manufacturer's Website: Qalsody                                                                                                                                   Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Radicava (edaravone)

Edaravone, sold as under the brand names Radicava and Radicut, is an intravenous medication used to help with recovery following a stroke and to treat amyotrophic lateral sclerosis (ALS)... Wikipedia

 

 

Manufacturer's Website: Radicava                                                                                                                                  Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

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