*Prices reflect U.S. average retail price

Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. It is taken by mouth.... Wikipedia

Manufacturer's Website: Cymbalta                                                                                                                 Average retail cost: $359/month

Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat major depressive disorder. It is recommended that the need for further treatment be occasionally reassessed. It may be less effective than its parent compound venlafaxine, although some studies have found comparable efficacy. It is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class and is taken by mouth... Wikipedia

Manufacturer's Website: Pristiq                                                                                                                    Average retail cost: $554/month

Milnacipran (trade names Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the US, but it is in other countries... Wikipedia

Manufacturer's Website: Savella                                                                                                                        Average retail cost: $556/month

Levomilnacipran (brand name Fetzima) is an antidepressant which was approved in the United States in 2013 for the treatment of major depressive disorder (MDD) in adults. It is the levorotatory enantiomer of milnacipran, and has similar effects and pharmacology, acting as a serotonin–norepinephrine reuptake inhibitor (SNRI)... Wikipedia

Manufacturer's Website: Fetzima                                                                                                                             Average retail cost: $585/month

Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder, and social phobia. It may also be used for chronic pain. It is taken by mouth... Wikipedia

Manufacturer's Website: EffexorXR                                                                                                                    Average retail cost: $699/month